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Kamagra – a drug for the treatment of ED

Table of Contents

    Understanding Kamagra: A Viagra Generic

    Kamagra is widely recognized as a reliable and well-tested generic form of Viagra, particularly popular for treating Erectile Dysfunction (ED). It is produced by Ajanta Pharma, headquartered in Mumbai, India, known globally for manufacturing generic medications.

    1) Kamagra – A Viagra Generic

    Generics are drugs containing the same amount of active ingredients as the original medications, with similar efficacy and safety. Developed based on previously confirmed efficacy and safety of active ingredients, generics have a shorter development period and can be offered at a lower price. These drugs undergo strict checks and trials by government institutions in each country and are approved for sale, assuring their reliability.

    Viagra was the world’s first ED medication, developed and launched by Pfizer Pharmaceuticals in 1998. Initially intended to treat angina, it was repurposed for ED treatment after clinical trials showed its effectiveness. Upon release, it was a sensation, famously known as the “dream drug” for its impressive impact on ED symptoms.

    2) Active Ingredient: Sildenafil

    Sildenafil, the active ingredient in Viagra, is used for maintaining erections in men with ED and treating certain heart conditions. It relaxes the muscles of blood vessel walls in the penis, enhancing and maintaining erections by inhibiting PDE-5 (phosphodiesterase-5), an enzyme causing erection issues. The effect of sildenafil typically starts within 30 minutes, but factors like diet, overall health, other medications, and physical condition can influence its duration and effectiveness.

    Kamagra Gold 100: Usage Instructions

    1) Timing of Consumption

    Kamagra Gold should be taken about an hour before sexual activity. Dosage varies (50 mg or 100 mg), and it’s crucial to split the 100 mg tablet if prescribed. Its active ingredients reach peak blood levels approximately one hour after intake.

    Kamagra Gold is not a daily medication but taken as needed. Diet greatly affects its efficacy, and it’s most effective on an empty stomach. If taken after a meal, it may not be fully effective. Wait at least 2 hours after eating before taking it. Avoid high-fat foods like tempura and grilled meat on days you plan to take Kamagra Gold.

    Moderate alcohol consumption may relax you, but excessive intake can reduce the drug’s effectiveness and lead to ED, so it’s best avoided.

    2) Dosage (50mg, 100mg)

    In Japan, the approved sildenafil doses are 25 mg and 50 mg, considering the physique of the Japanese. The 100 mg dose common abroad is too high for an average Japanese. First-time users should start with 25 mg. If you have a 100 mg tablet, use a pill cutter to split it into halves or quarters.

    Kamagra Gold 100: Maximum Monthly Usage

    The recommended dose is one tablet per day (up to 50 mg or half a tablet of 100 mg), with a maximum of 30 tablets per month. Continuous daily use is not advised. If sexual activity is planned more than twice a week, consider taking 5 mg Cialis (or its generic equivalent) daily, adjustable to 2.5 mg based on individual response. Consult your doctor for detailed advice.

    Kamagra Gold 100: Efficacy and Duration

    Kamagra Gold belongs to PDE-5 inhibitors. In a healthy body, sexual stimulation triggers nitric oxide release in the penis, activating guanylate cyclase and producing cGMP (cyclic guanosine monophosphate), leading to an erection. In ED, PDE-5 is prematurely released, disrupting this process. PDE-5 inhibitors prevent this disruption, aiding in maintaining erections.

    The effect of Kamagra Gold lasts about 4 hours, extendable up to 5 hours depending on individual constitution. Higher doses prolong the effect but also increase the risk of side effects, so always adhere to the doctor-recommended dose suited to your constitution and symptoms.

    Kamagra Gold: Time of Effect Post-Consumption

    Kamagra Gold 100: Side Effects

    Common side effects include dizziness, headache, facial flushing, stomach discomfort, vision changes (like sensitivity to light, blurred vision, and difficulty distinguishing blue and green colors). If any of these persist or worsen, immediately consult your doctor or pharmacist.

    Taking an excessive dose increases the risk of side effects. Always follow the doctor-prescribed dosage.

    Common Side Effects

    • Nosebleeds
    • Headaches
    • Stomach upset
    • Facial flushing
    • Insomnia
    • Heating sensation
    • Prolonged erection
    • Respiratory infection
    • Nausea
    • Vomiting
    • Bronchitis
    • Sore throat
    • Runny or stuffy nose

    Serious Side Effects

    Seek immediate medical help if experiencing serious side effects, such as symptoms caused by low blood pressure (blurred vision, dizziness, fainting, lightheadedness, nausea or vomiting, drowsiness, weakness, shortness of breath, priapism, vision disturbances, increased intraocular pressure, hearing issues, heart problems like chest pain, shortness of breath, dizziness, confusion, acute cardiovascular diseases, ventricular arrhythmia).

    Kamagra Gold 100: Precautions for Use

    1) Individuals with Chronic Conditions

    Kamagra Gold can reduce optic nerve blood supply, causing sudden vision disturbances. Though rare, people with heart disease, high blood pressure, diabetes, high cholesterol, or existing eye diseases should consult a doctor before taking this product.

    Consult a doctor if you have any of the following:

    • Heart diseases (e.g., heart attack, life-threatening irregular heartbeat, chest pain/angina, heart failure in the past 6 months)
    • Kidney or liver disease
    • High or low blood pressure
    • Penile conditions (e.g., Peyronie’s disease)
    • History of prolonged erections
    • Sickle cell anemia, leukemia, multiple myeloma
    • Eye diseases (e.g., pigmentary retinitis, sudden vision loss, NAION, etc.)

    2) People with Allergies

    Inform your doctor or pharmacist if you have allergies before taking Kamagra Gold. It may contain inactive ingredients causing allergic reactions or other problems. Consult your pharmacist for details.

    3) Drug Interactions to Avoid with Kamagra Gold

    Drug interactions can increase the risk of serious side effects. This information doesn’t include all possible drug interactions, so make a list of all products you take (including prescription/non-prescription drugs and herbal products) and share it with your doctor or pharmacist.

    Avoid combining Kamagra Gold with Riociguat (Adempas). It can significantly lower blood pressure when taken with nitrate medications, leading to dizziness, fainting, and in rare cases, heart attack or stroke. Avoid it with medications for angina (nitrates like nitroglycerin, isosorbide), amyl nitrates, amyl nitrite.

    If you’re taking alpha-blockers (like doxazosin, tamsulosin) for enlarged prostate or high blood pressure, your blood pressure could become too low, causing dizziness and fainting. Doctors typically prescribe lower sildenafil doses to minimize the risk of low blood pressure for patients on alpha-blockers.

    Other medications to avoid in combination:

    • Azole antifungals (e.g., itraconazole, ketoconazole)
    • Macrolide antibiotics (e.g., clarithromycin, erythromycin)
    • HIV protease inhibitors (e.g., ritonavir, saquinavir)
    • Hepatitis C virus protease inhibitors (e.g., boceprevir, telaprevir)
    • Mifepristone
    • Sildenafil or other ED medications, pulmonary hypertension drugs (tadalafil, vardenafil, etc.)

    4) Avoid Grapefruit and Its Juice

    Grapefruit and its juice contain furanocoumaric acid, which suppresses the gradual breakdown and elimination of sildenafil, Kamagra Gold’s active ingredient, from the body. This can lead to excess absorption and retention of the active ingredient, causing serious side effects. Among citrus fruits, lemon doesn’t contain furanocoumaric acid and can be consumed while taking Kamagra Gold.

    5) Storage Method

    Store away from high temperatures and humidity in a cool place. Keep out of reach of children and pets.

    Kamagra Gold and Alcohol Compatibility

    Sildenafil, the active ingredient in Kamagra and Viagra, interacts poorly with alcohol. It’s advisable to avoid alcohol while taking Kamagra.

    If you’re nervous before sex, limit alcohol to one glass of a light drink like beer or wine. Excessive drinking can disrupt medication absorption, reducing effectiveness or causing strong side effects that may discourage sexual activity.

    Kamagra Gold’s Effect on Women

    Kamagra Gold is an ED medication for men. While some women attempt to use Viagra, clinical trials haven’t been conducted on women, so it’s probably safer not to try it.

    Medications like Cenforce FM and Lovegra, designed and manufactured for women, contain the same active ingredient, sildenafil, as Kamagra Gold, and are recommended for use.

    Fliban, a generic version of Addyi, treats hypoactive sexual desire disorder (HSDD) in women. Its active ingredient, flibanserin, became a hot topic in 2015 when first approved by the FDA for treating women’s HSDD.