Understanding Cialis: A Comprehensive Guide
What is Cialis?
Cialis is a medication used to treat Erectile Dysfunction (ED) in men, containing the active ingredient Tadalafil. Developed as the latest in a series of ED treatments, Cialis stands out for its minimal side effects, reduced food influence, and extended duration of effect. As of August 2013, it held a 42% global market share, making it a leader in the industry. Nicknamed the “weekend pill” due to its prolonged effect, it is a preferred choice for many.
Eli Lilly: The Pharmaceutical Company Behind Cialis
Cialis was developed and is manufactured by the American pharmaceutical company Eli Lilly and Company. It received FDA approval in November 2003. The headquarters of Eli Lilly is in Indianapolis, Indiana. In Japan, Cialis was approved in July 2007. Its recommended use is as an on-demand medication, but it can also be taken daily in smaller doses (5 mg and 2.5 mg) to enjoy sexual activity anytime.
The Function of the Active Ingredient Tadalafil
Tadalafil, the active ingredient in Cialis, is used for treating ED. It helps create an erection by relaxing the penile muscles and increasing blood flow when a man is sexually stimulated. Classified as a PDE5 (Phosphodiesterase 5) inhibitor, it maintains an erection by inhibiting PDE5. Tadalafil is also used for treating symptoms of benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension (PAH).
Understanding ED (Erectile Dysfunction)
Erectile Dysfunction, or ED, is a condition where a man has trouble achieving or maintaining an erection sufficient for sexual intercourse. It is reported that 30 million men worldwide suffer from ED. ED can range from a total inability to achieve an erection to a tendency to sustain only brief erections.
Generic Cialis
The anticipation for generic versions of Cialis has been high. In 2018, Teva Pharmaceutical Industries gained exclusive rights to sell Tadalafil tablets in the US for 180 days. In 2019, several other companies, including Accord Healthcare and Cipla, received FDA approval for Tadalafil tablets. The availability of generic Cialis varies by country due to exclusive marketing rights.
Cialis 20 mg – The Maximum Dosage
The recommended limit is one tablet per day and a maximum of 30 tablets per month. Continuous daily intake of 10 mg and 20 mg doses is not advised. For those planning sexual activity at least twice a week, a daily dose of 5 mg is recommended, which can be adjusted down to 2.5 mg.
Efficacy of Cialis
Cialis belongs to the PDE5 inhibitor class, similar to Viagra and Levitra. It helps maintain higher levels of cGMP by inhibiting PDE5, assisting in maintaining a satisfactory erection. Cialis has a unique chemical structure, which might be beneficial for those who experience side effects from Viagra or Levitra.
How to Take Cialis
Cialis should be taken at least an hour before sexual activity, with its active ingredients absorbing into the body in about 30-60 minutes. The effect varies from person to person, typically taking 1 to 4 hours. It can be taken as needed, but not more than once in 24 hours.
Dosage Variations of Cialis
Cialis is available in 5, 10, and 20 mg doses. For first-time users, a starting dose of 5 or 10 mg is recommended. Adjustments can be made based on individual response, with a maximum of 20 mg per dose. People planning frequent sexual activity can take a daily dose of 5 mg, adjustable to 2.5 mg based on response. Cialis Daily, a lower dose taken daily, is not officially approved in Japan.
Cialis and Food Interaction
Cialis is less affected by food intake. It’s best taken on an empty stomach. If taken after a meal, it should be a light, low-fat meal, with Cialis taken 1-2 hours before or 2 hours after the meal.
Table Summarizing Information on Cialis
| Aspect | Detail |
|---|---|
| Active Ingredient | Tadalafil |
| Use | Treatment of Erectile Dysfunction (ED), Benign Prostatic Hyperplasia (BPH), Pulmonary Arterial Hypertension (PAH) |
| Company | Eli Lilly and Company |
| FDA Approval | November 2003 |
| Dosage Forms | 5 mg, 10 mg, 20 mg |
| Maximum Dosage | 20 mg per day |
| Food Interaction | Minimal, best taken on an empty stomach |
| Time to Effect | 30-60 minutes, with full effect in 1-4 hours |
| Generic Availability | Varies by country |
| Market Share (as of 2013) | 42% globally |
FAQ
1. What is Cialis used for?
Cialis is primarily used to treat Erectile Dysfunction (ED) in men. It also helps in managing symptoms of benign prostatic hyperplasia (BPH) and treating pulmonary arterial hypertension (PAH).
2. Who manufactures Cialis?
Cialis is developed and manufactured by the American pharmaceutical company Eli Lilly and Company.
3. How does Cialis work?
Cialis works by relaxing the muscles of the penis and increasing blood flow during sexual stimulation. It inhibits the enzyme PDE5, which is responsible for regulating blood flow in the penis.
4. What is the maximum dosage of Cialis?
The maximum recommended dosage of Cialis is 20 mg per day.
5. Can Cialis be taken with food?
Yes, Cialis can be taken with or without food. However, it is best taken on an empty stomach for quicker absorption.
6. Are there generic versions of Cialis?
Yes, generic versions of Cialis are available. Their availability varies by country and depends on marketing rights.
7. How long does it take for Cialis to take effect?
Cialis typically takes 30-60 minutes to start working, with the full effect felt in 1-4 hours, depending on the individual.
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